Global Sequencing Reagents Market by End Use (Academic & Clinical Research), by Technology (NGS, TGS), by Application (Clinical Investigation, Oncology) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast To 2028

Summary of the Report

Global sequencing reagents market was valued at USD4.5 billion in 2018. It is expected to grow at a CAGR 13.7% during the forecast period. The market benefits from continuous developments in sequencing technologies that provide high throughput data for large scale genomic research. Researchers can sequence the entire genome in a shorter time and at a lower price by using novel technologies such as Nanopore or Single-Molecule-Real-Time (SMRT). Market development is driven by the availability of commercial kits that provide reagents specific to sequencing applications.

Automation and streamlining of workflow have reduced the time taken to prepare the library. Tagmentation in library preparation also combines genome fragmentation and adaptor ligation into one step. This technique can be integrated into existing sequencing protocols to simplify workflow, reduce cost and improve data quality.

The exponential decline in the cost of genetic sequencing from USD 10-15 million per gene in 2001 to USD 1200 per genome for 2017 has fueled the growth of sequencing technologies and the use of sequencing reagents. In recent years, the cost of installing sequencing platforms has dropped significantly due to this reduction.

Supportive government programs have aided in the expansion of genome sequencing, which identifies the genetic variations that are associated with human diseases. In December 2018, for example, NHS England and Genomics England sequenced 100,000 genomes from NHS patients in order to discover new treatments and diagnoses for patients with rare inherited disorders and cancer.

Additionally, funding from both public and private sources has aided in the growth of high-throughput technology. This has subsequently increased demand for their respective agents. In March 2018, for example, the German Research Foundation provided USD 17.3 million to four German sequencing centers in order to equip them with NGS technology.

Technology Insights

NGS occupied a significant market share in 2018. NGS accounted for a significant market share in 2018. This is due to the fact that it has become a standard practice in molecular diagnostics and molecular pathology as well as other clinical research applications. NGS platforms also offer greater discovery power for rare or novel variants due to their deep sequencing approach.

NGS technology is well-suited for personalized medicine and companion diagnostics for chronic diseases. This allows for the development of more effective, targeted, and complex drugs and allows clinicians to adopt NGS platforms in-vitro diagnostics.

The lucrative growth rate of this sector is responsible for a rise in demand for third-generation sequencing technologies. Genome sequencing has been made faster and more reliable by the advent of TGS. Scientists can now initiate re-sequencing the genome that has been sequenced, to achieve a higher level accuracy. Using the SMRT technique, Escherichia coli can now be sequenced with a 99.99% accuracy.

Insights on Reagent Type

In 2018, the sequencing kits segment was the dominant market by revenue and will continue to be so throughout the forecast period. The presence of high-throughput platforms like the MiniSeq and MiSeq from Illumina, NextSeq and HiSeq X series from Illumina; PGM and IonS5 systems from Thermo Fisher Scientific; as well as PGM, IonS5, Ion Proton systems from Thermo Fisher Scientific; MinION, GridION X5, PromethION and PromethION by Oxford Nanopore.

In the next few years, library kits will be a significant market segment due to constant improvements in library preparation workflow. High-quality libraries can be created by using liquid handling platforms.

Application Insights

The largest market share for sequencing reagents in 2018 was held by Oncology due to its high use rate for clinical research and development of therapeutics and diagnostics. Oncologists have been able to quickly access the genetic information and heterogeneity related to cancer and other cancer-related genes thanks to rapid advancements in sequencing capabilities.

NGS analysis of tumor transcriptomics, genomes, epigenomics and epigenomics is positively impacting biomarker discovery and cancer diagnosis. The development of precision oncology has been made possible by the enhancement of sequencing capabilities. This allows for new clinical trials to detect genetic vulnerabilities in patients.

High-throughput technologies and bioinformatics allow for the identification of pathogens, which allows for in-depth analysis of antimicrobial resistance, disease transmission, and virulence. This is the reason for the widespread adoption of reagents within the field of clinical microbiology and public health microbiology. The fastest expected growth is in the clinical investigation segment during the forecast period.

End-use Insights

The market can be divided by end-use into clinical research, academic research, hospitals and clinics and pharmaceutical and biotechnology firms. The largest share of revenue was captured by academic research due to the existence of many universities and research centers that offer courses in molecular biology using NGS techniques. These centers offer scholarships for Ph.D. projects in NGS. This will drive NGS reagent demand.

Over the forecast period, the segment of clinical research is expected to experience the most rapid growth. This segment is expected to see a rise in the use of high-throughput technology-based diagnostic test that have been cleared by CLIA or are currently under clinical approval. For clinical applications and research, the traditional Sanger method with its associated reagents is still widely used. NGS reagents are becoming more popular in clinical diagnostics. Their single-nucleotide resolution allows for the detection of the smallest mutations (SNPs) without the need to provide additional information. Recent technological advances have made it possible to detect both larger abnormalities as well as SNPs.

Regional Insights

North America was the dominant market for revenue in the global market and will continue to enjoy the greatest growth over the forecast period. This is due in part to the simultaneous development of both established and emerging players to expand their reagents range. Clonal Technology has reflected this trend by launching NGS library preparation kits in September 2018. Asia Pacific is poised to experience significant growth. The technological integration of high-throughput technologies has been possible thanks to significant investments in genetics research in Japan and China. This has facilitated the adoption of sequencing technology in Asia Pacific.

Market Share insights on Sequencing Reagents

Thermo Fisher Scientific, Inc., Illumina, Inc., QIAGEN, BGI; Pacific Biosciences of California, Inc., F. Hoffmann-La Roche AG, Oxford Nanopore Technologies, Agilent Technologies, Agilent Technologies, Fluidigm Corporation, ArcherDX, Inc., Takara Bio Inc., and Bioline are some of the prominent players in this market.

Market players are investing significant amounts to increase their market presence and keep their competitive edge. Key companies also participate in collaboration models, product development and geographic expansion strategies in untapped areas. In March 2019, Agilent Technologies launched Magnis NGS Prep System, a new library preparation method for NGS technology. The new system features reagents, protocols, and tools that allow you to quickly and easily analyze complex genetic aberrations as well as multiple genes from the genomic DNA.

Market Report Scope Sequencing Reagents

The Report Covers Certain Segments

This report provides a forecast of revenue growth at the global, regional and country level and analyzes the most recent industry trends in each sub-segment from 2015 to 2026. Grand View Research segmented this global market report on sequencing reagents based on technology, type, application, end use, and region.

• Technology Outlook (Revenue USD Million, 2015-2026)

  • Sanger Sequencing

  • Next-Generation Sequencing

  • Third Generation Sequencing

• Outlook for Reagent Type (Revenue, USD million, 2015-2026)

  • Library Kits

  • Template kits

  • Control Kits

  • Sequencing Kits

  • Other

• Application Outlook (Revenue USD Million, 2015-2026)

  • Oncology

  • Reproductive Health

  • Clinical Investigation

  • Agrigenomics & Forensics

  • Other

• End-use Outlook (Revenue USD Million, 2015-2026)

  • Academic Research

  • Clinical Research

  • Hospitals & Clinics

  • Companies in Pharmaceutical & Biotechnology

  • Other

• Regional Outlook (Revenue USD Million, 2015-2026)

  • North America

    • The U.S.

    • Canada

  • Europe

    • Germany

    • U.K.

  • Asia Pacific

    • China

    • Japan

  • Latin America

    • Brazil

  • The Middle East and Africa (MEA).

    • South Africa

These are the most frequently asked questions about this report

b. Global sequencing reagents market was valued at USD 5.2 Billion in 2019, and is forecast to grow to USD 5.9 Billion by 2020.

b. Global sequencing reagents markets are expected to expand at a compound annual rate of 13.7% between 2019 and 2026, reaching USD 12.6 billion in 2026.

b. With a market share of 59.3%, the next-generation sequencing segment (NGS), dominated the sequencing agents market in 2019. NGS is a popular practice in molecular diagnostics and molecular pathology.

b. Thermo Fisher Scientific, Inc., Illumina, Inc., QIAGEN, BGI; Pacific Biosciences of California, Inc., F. Hoffmann-La Roche AG, Oxford Nanopore Technologies, Agilent Technologies, Fluidigm Corporation, ArcherDX, Inc., Takara Bio Inc., and Bioline are some of the key players in the sequencing market.

b. Market growth is driven by decreasing genetic sequencing costs, rising demand for third-generation sequencing and the presence of many funding programs. There has also been an increase in competition among prominent market players.

Up Market Research published a new report titled “Sequencing Reagents Market research report which is segmented by End Use (Academic & Clinical Research), by Technology (NGS, TGS), by Application (Clinical Investigation, Oncology), By Players/Companies Inc; F Hoffmann-La Roche AG; Oxford Nanopore Technologies; Agilent Technologies, Inc; QIAGEN; BGI; Pacific Biosciences of California, Thermo Fisher Scientific, Inc; Fluidigm Corporation; ArcherDX, Inc; Illumina, Inc; Takara Bio Inc; and Bioline”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.

Report Scope

The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.

Global Sequencing Reagents Market Report Segments:

The market is segmented by End Use (Academic & Clinical Research), by Technology (NGS, TGS), by Application (Clinical Investigation, Oncology).

Sequencing Reagents Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.

Key Benefits for Industry Participants & Stakeholders:

• Industry drivers, restraints, and opportunities covered in the study
• Neutral perspective on the market performance
• Recent industry trends and developments
• Competitive landscape & strategies of key players
• Potential & niche segments and regions exhibiting promising growth covered
• Historical, current, and projected market size, in terms of value
• In-depth analysis of the Sequencing Reagents Market

Overview of the regional outlook of the Sequencing Reagents Market:

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.

Highlights of The Sequencing Reagents Market Report:

1. The market structure and projections for the coming years.
2. Drivers, restraints, opportunities, and current trends of Sequencing Reagents Market.
3. Historical data and forecast.
4. Estimations for the forecast period 2028.
5. Developments and trends in the market.

                1. Academic & Clinical Research

                1. NGS

                2. TGS

                1. Clinical Investigation

                2. Oncology

9. Market scenario by region, sub-region, and country.
10. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
11. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
12. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Sequencing Reagents Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.

How you may use our products:

• Correctly Positioning New Products
• Market Entry Strategies
• Business Expansion Strategies
• Consumer Insights
• Understanding Competition Scenario
• Product & Brand Management
• Channel & Customer Management
• Identifying Appropriate Advertising Appeals

Reasons to Purchase the Sequencing Reagents Market Report:

• The report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period
• Segments and sub-segments include quantitative, qualitative, value (USD Million,) and volume (Units Million) data.
• Regional, sub-regional, and country level data includes the demand and supply forces along with their influence on the market.
• The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
• Comprehensive companies offering products, relevant financial information, recent developments, SWOT analysis, and strategies by these players.