Global Perfusion System Market by Technology (Normothermic Machine Perfusion, Hypothermic Machine Perfusion), by Organ Type (Heart, Liver, Kidney, Lung) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast To 2028

Summary of the Report

Global perfusion market was worth USD 87.05 millions in 2016. It is expected to grow at 8.7% CAGR during the forecast period. Over the forecast period, the increasing number of organ failures will drive up the demand for transplantation procedures.

Organ supply is the main problem with these procedures. Two preservation methods can be used to address this issue: Machine Perfusion (MP), and Static Cold Storage. Although SCS is an extremely popular preservation method, it is not efficient enough to preserve high-risk organs. Hypothermic Machine Perfusion (HMP), has been developed to address these problems.

U.S. perfusion market by technology, 2014-2025 (USD million).

Market growth is driven by a rising demand for transplantation, which is a result of the growing incidence of chronic illnesses. A growing number of organ diseases is driving the demand for more cost-effective preservation solutions. The National Institute of Diabetes and Digestive and Kidney Diseases, (NIH) has published statistics that show approximately 661,000 Americans are suffering from kidney disease. This number is expected to rise over the forecast period.

Transplantation is a viable treatment for organ failure. Due to recent high success rates in transplantation, the demand for organs is on the rise. Statistics from the Centre for Disease Control (CDC) show that 75,000 people waited for organ donation in 2014. However, only 8,000 deceased donors were made.

Unexpected shortages have resulted from the inability to find donors to meet increasing demand. According to the National Kidney Foundation, there were 121,678 Americans waiting for transplantation as of November 2016. This has led to an increase in mortality which has prompted a surge in demand for perfusion systems that can improve the organ's viability.

Due to lack of transport and preservation facilities, organs donated are often not available for surgical procedures. These technologies allow for enhanced preservation which extends its shelf life and improves patient outcomes. These factors have a direct impact on the overall market growth for perfusion systems.

Technology Insights

HMP accounted for a large percentage of MP technologies in 2016, due to its associated benefits. Because it allows for viability of grafts prior to transplantation, HMP is an established alternative to cold storage in kidney preservation. It is useful in kidney transplant surgery to increase patient survival rates and improve the quality of grafts. It also provides a platform to recover grafts prior to surgery.

HMP is being tested for transplantation to other organs, such as the liver. It maintains a steady flow of antioxidants, metabolic substrates, and flushes the liver of toxins, proteins, and cytokines. It reduces the reperfusion damage caused by a statically stored liver.

To curb rising demand for warm-blood perfusion, Normothermic MP techniques will be more popular in the future. Perfusion at Normal Body Temperature is available in ex-situ as well as in-situ regional perfusion.

Reperfusion lesions can occur after liver transplantation from a diseased donor. This increases the likelihood of hepatocellular cancer recurrence. NMP combined with Extracorporeal Mesh Oxygenation(ECMO) reduces the chance of cancer recurrence and prevents reperfusion. These benefits associated with NMP will be a growth engine in the near future.

Organ Type Insights

Because kidney transplantation is a popular option, kidney failure rates are rising due to the increasing prevalence of Chronic Kidney Disease (CKD), a large share of the market was held by this segment. These MP devices were most commonly used to preserve kidneys, and they dominated the market in 2016.

LifePort Kidney Transporter, WAVESRM3 by Waters Medical Systems and Airdrive hypothermic renal perfusion transport system are the most popular MP systems for kidneys.

The growth in R&D to find cost-effective and feasible solutions to heart transplantation is expected to drive MP for heart transplant to grow significantly over the forecast period. This industry has the potential to grow because of the ongoing research into developing novel technologies for heart.

As the demand for MP procedures is growing, they will be implemented in the forecast period. OCS Lungs, Vivoline LS1, Lung Assist and Organ Assist B.V. are the available MP devices for lungs.

Regional Insights

Due to growing demand for transplant surgery, North America had the largest share of organ perfusion system installations in 2016. The U.S. Department of Health and Human Services reports that there are over 119,000 people who are waiting to be transplanted. Only 2,555 donors were available in April 2017. This number is expected to rise over the next few years.

A major public health problem is the growing gap between supply and demand. To meet this unmet demand, it is necessary to increase the number of initiatives that promote donations. The government of the United States is taking various steps to encourage donation. The White House organized the Organ Summit in 2016 to highlight the steps that can be taken to reduce the waiting list for transplantation.

2016 (%)

Due to rising rates of chronic diseases and increased demand for organ donation, the Asia Pacific region market for MP will grow at the fastest CAGR. Both developed and developing countries encourage people to donate organs. To promote donation, the Ministry of Health & Family Welfare of India, for instance, has taken a number of steps. To encourage donations, the government implemented the National Organ Transplant Programme.

The government also agreed to provide financial support for the establishment regional organ and tissue transplant organizations. The presence of non-profit organizations like Donate Life America, which promotes organ donor in collaboration with American Hospital Association, is another important factor in perfusion systems market.

Market Share Analysis for Perfusion Systems

The market participants include XVIVO Perfusion AB, Organ Assist B.V., Organ Recovery Systems, Organ Transport Systems, Waters Medical Systems, Paragonix Technologies, Inc., TransMedics, Inc., OrganOx Limited, and Bridge to Life Ltd.

The growing demand for transplantation is giving this industry a boost. This has drawn many local and international players into the market. This growth can be attributed to the growing demand for technologically advanced products that enhance ex vivo perfusion.

Market competition is strong with key players actively involved in product development and partnerships to increase market penetration. In the near future, industry rivalry will be heightened by the increasing number of MP system dealers and distributors.

Industries are actively involved in R&D. During the forecast period, approval is expected for many products that are currently undergoing clinical trials in Europe and the U.S. The market will experience high levels of competition due to the above factors.

Perfusion System Market Report Scope

The Report Covers Certain Segments

This report predicts revenue growth at the global, regional, and country levels. It also analyzes the industry trends for each sub-segment from 2014 through 2025. Grand View Research has divided the global perfusion market based on technology, organ type and location.

• Technology Outlook (Revenue USD Million, 2014-2025)

  • Hypothermic

  • Normothermic

• Organ Type Outlook (Revenue USD Million, 2014-2025)

  • Heart

  • Lung

  • Kidney

  • Liver

  • Other

• Regional Outlook (Revenue USD Million, 2014-2025)

  • North America

    • The U.S.

    • Canada

  • Europe

    • The U.K.

    • Germany

  • Asia Pacific

    • Japan

    • China

  • Latin America

    • Brazil

    • Mexico

  • The Middle East and Africa

    • South Africa

These are the most frequently asked questions about this report

b. Global perfusion system market was valued at USD 111.0 Million in 2019, and is forecast to grow to USD 120.5 Million in 2020.

b. Global perfusion systems market will grow at 8.7% compound annual growth rate from 2018 to 2025, reaching USD 183.8 million in 2025.

b. With a 38.6% share in 2019, North America was the dominant market for perfusion systems. This can be attributed to the growing demand for transplant surgery as well as government initiatives.

b. XVIVO Perfusion AB, Organ Assist B.V., Organ Recovery Systems, Organ Transport Systems, Waters Medical Systems, Paragonix Technologies, Inc., TransMedics, Inc., OrganOx Limited, and Bridge to Life Ltd. are some of the key players in the perfusion systems market.

b. Market growth is driven by technological advances, increasing organ donation and growing demand.

Up Market Research published a new report titled “Perfusion System Market research report which is segmented by Technology (Normothermic Machine Perfusion, Hypothermic Machine Perfusion), by Organ Type (Heart, Liver, Kidney, Lung), By Players/Companies XVIVO Perfusion AB; Organ Assist BV; Organ Recovery Systems; Organ Transport Systems; Waters Medical Systems; Paragonix Technologies, Inc; OrganOx Limited; and Bridge to Life Ltd, Inc; TransMedics”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.

The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.

Global Perfusion System Market Report Segments:

The market is segmented by Technology (Normothermic Machine Perfusion, Hypothermic Machine Perfusion), by Organ Type (Heart, Liver, Kidney, Lung).

Perfusion System Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.

Key Benefits for Industry Participants & Stakeholders:

• Industry drivers, restraints, and opportunities covered in the study
• Neutral perspective on the market performance
• Recent industry trends and developments
• Competitive landscape & strategies of key players
• Potential & niche segments and regions exhibiting promising growth covered
• Historical, current, and projected market size, in terms of value
• In-depth analysis of the Perfusion System Market

Overview of the regional outlook of the Perfusion System Market:

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.

Highlights of The Perfusion System Market Report:

1. The market structure and projections for the coming years.
2. Drivers, restraints, opportunities, and current trends of Perfusion System Market.
3. Historical data and forecast.
4. Estimations for the forecast period 2028.
5. Developments and trends in the market.

                1. Normothermic Machine Perfusion

                2. Hypothermic Machine Perfusion

                1. Heart

                2. Liver

                3. Kidney

                4. Lung

8. Market scenario by region, sub-region, and country.
9. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
10. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
11. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Perfusion System Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.

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Reasons to Purchase the Perfusion System Market Report:

• The report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period
• Segments and sub-segments include quantitative, qualitative, value (USD Million,) and volume (Units Million) data.
• Regional, sub-regional, and country level data includes the demand and supply forces along with their influence on the market.
• The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
• Comprehensive companies offering products, relevant financial information, recent developments, SWOT analysis, and strategies by these players.