Global Next Generation Sequencing Sample Preparation Market by Workflow (Automated Library Preparation) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast To 2028

Industry Insights

Global next-generation sequencing (NGS), sample preparation market was worth USD 2.76 billion in 2018. It is forecast to grow at an annual CAGR of 11.19% over the forecast period. Product development that allows for the creation of high-quality libraries and sufficient yields for successful sequencing can explain the anticipated revenue growth.

The boundaries of sample preparation protocols are being expanded due to the advancements in sequencing technologies that allow for capacity expansion. High quality sequencing data can be generated by efficient pre-sequencing steps like library preparation and target enrichment. The NGS sample preparation market is thriving because of the constant innovation in this field. Standardized sample preparation protocols have been developed.

Large-scale laboratories are faced with a lot of data and it has made tracking and organizing sequencing data a challenge. The market has seen a significant increase in electronic solutions for managing NGS samples.

Electronic solutions can include electronic lab notebooks (ELNs), spreadsheets and automation. Additionally, NGS samples can be tagged with genetic (DNA), barcodes during library preparation to allow for efficient tracking of sample reads back to original types.

Automation in NGS sample preparation has been possible due to the evolution of automated and integrated informatics as well as mechanical protocols. Automation has had a significant impact on the NGS sample preparation market. It increases sequencing speed and capacity as well as sample tracking. Automated robots are able to locate reagents quickly and perform operations on the sample according to the system requirements. The system also includes cameras and lasers that allow for easy identification of samples during each stage of sequencing.

Companies also want to speed up the preparation of high-quality libraries. Key players are involved in developing efficient sample preparation protocols that guarantee the success of sequencing, regardless of input. PerkinElmer used artificial intelligence to improve its NGS workflow. IntelliChip technology from PerkinElmer minimizes variation and standard deviations for different assay runs, optimizing the entire process.

PerkinElmer also collaborated 10X Genomics in order to improve the extraction and quantification of various types of input materials. This collaboration was to combine PerkinElmer’s LabChip Touch Nucleic Acid Anazer with 10x Genomics’ Chromium Genome Solution, as well as chemagic technology, to create an automated workflow for sample preparation.

Workflow insights

Semi-automated library prep was the most popular in 2018, and it is expected to continue to dominate the market for the entire forecast period. Combining manual and automated library preparation methods is the reason for this. Automation is used to ligate molecular barcoded adaptationors, end repair and purification reactions. This allows for ligation SOLiD adaptors onto the processed DNA.

Semi-automated library preparation processes include library amplification and gel purification. Segment growth will also be driven by the introduction of automated library preparation methods. Automation that requires minimal human intervention to implement complex library preparation protocols will enable labs to be more productive and reduce their staffing. It is necessary to find a way to increase adoption of automated protocols in laboratories that are unable or unwilling to purchase a robot.

Application Insights

The largest share of the 2018 market was in the oncology segment, due to the presence several players involved in the development and maintenance of targeted panels for oncology. These panels are able to determine the need for sample preparation solutions. For the development of companion diagnostics products for oncology, companies are teaming up with leading companies.

In April 2018, Illumina partnered with Bristol-Myers Squibb in order to produce and market companion diagnostics assays that could be used for oncology immunotherapies. Loxo Oncology partnered with Illumina in April 2018 to develop NGS-based companion diagnostic solutions for solid tumours.

Other market players are also trying to expand their product lines for companion diagnostics in oncology. Biodesix, Inc., a company that develops NGS tests for non-small cell lung cancer (NSCLC), signed an agreement in July 2019 with Thermo Fisher Scientific. The company is also seeking FDA-Premarket approval (PMA), for the test.

End-Use Information

The highest projected CAGR for the clinical research segment will be during the forecast period. This is due to NGS's high use in cancer research, particularly in the discovery and study of cancer-related genes, tumor heterogeneity and identification of mutations that cause tumorigenesis. The increase in funding for NGS technology by government agencies will boost revenue generation.

This segment will also benefit from the availability of clinical research solutions via market entities like Illumina, Thermo Fisher Scientific Corporation and Agilent Technology for target enrichment and detection. TruSight RNA Fusion and TruSight Tumor 170 are the most prominent cancer research panels from Illumina. TruSight Tumor 15 TruSight Tumor 15, TruSight Tumor 15, TruSight Tumor 15, TruSight Tumor 15, TruSight Tumor 15, TruSight Myeloid Sequencing Panel and TruSight Cancer Sequencing Panel are also available.

Regional Insights

North America was the dominant market for revenue, accounting for the majority of global market space revenues. It is expected that it will continue to hold this position in the future. The projected market growth is due to the simultaneous development of next generation sequencing, personalized medicines and companion diagnostics in this region.

The region's biotechnology and ancillary market is also being driven by high R&D investments, a technologically advanced healthcare research system, and substantial players.

This market is expected to grow significantly in Asia, second only to North America. The expected growth trend is due to changes in regulatory structures, affordability patterns and technological advancements in developing economies in this region. The region's diseased population also increases clinical trials and drives demand for NGS solutions.

Next-Generation Sequencing Sample Prepared Market Share Insights

Agilent Technologies is one of the key players in this market. BGI; Biomatters Ltd., Bio-Rad Laboratories Inc.; DNASTAR; Eurofins Scientific. F. Hoffmann-La Roche Ltd. Foundation Medicine. Partek Incorporated. Parkin Elmer. PierianDx. QIAGEN. Quest Diagnostics Incorporated. and Thermo Fisher Scientific.

These companies are involved in product development and strategic alliances to keep their market share. Collaborations with other companies involved in NGS technology workflow, including data analysis and sequence sequencing, would help to increase the use of this technology for diagnosing and prognosing chronic diseases.

The Report Covers Certain Segments

This report provides a forecast of revenue growth as well as an analysis of market trends in each submarket from 2014 to 2025. Grand View Research, Inc. analyzed the global next-generation sequencing market report based on workflow, application, end uses, and location.

• Workflow Outlook (Revenue USD Million, 2014-2025)

  • NGS Library Preparation kits

  • Semi-automated Library Preparation

  • Automated Library Preparation

  • Clonal Amplification

• App Outlook (Revenue USD Million, 2014-2025)

  • Oncology

  • Clinical Investigation

  • Reproductive Health

  • HLA Typing/Immune System Monitoring

  • Metagenomics, Epidemiology & Drug Development

  • Agrigenomics & Forensics

  • Consumer Genomics

• End-Use Outlook (Revenue USD Million, 2014-2025)

  • Academic Research

  • Clinical Research

  • Hospitals & Clinics

  • Pharma & Biotech Entities

  • Other users

• Regional Outlook (Revenue USD Million, 2014-2025)

  • North America

    • U.S.

    • Canada

  • Europe

    • Germany

    • UK

  • Asia Pacific

    • Japan

    • China

  • Latin America

    • Brazil

  • MEA

    • South Africa

Up Market Research published a new report titled “Next Generation Sequencing Sample Preparation Market research report which is segmented by Workflow (Automated Library Preparation), By Players/Companies Agilent Technologies; BGI; Biomatters Ltd; Bio-Rad Laboratories, Inc; Congenica Ltd; DNASTAR; Eurofins Scientific; F Hoffmann-La Roche Ltd; Foundation Medicine; Genomatix GmbH; Illumina; Macrogen; Myriad Genetics; Oxford Nanopore Technologies; Pacific Biosciences of California; Partek Incorporated; Perkin Elmer; PierianDx; QIAGEN; Quest Diagnostics Incorporated; and Thermo Fisher Scientific”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.

Report Scope

The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.

Global Next Generation Sequencing Sample Preparation Market Report Segments:

The market is segmented by Workflow (Automated Library Preparation).

Next Generation Sequencing Sample Preparation Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.

Key Benefits for Industry Participants & Stakeholders:

• Industry drivers, restraints, and opportunities covered in the study
• Neutral perspective on the market performance
• Recent industry trends and developments
• Competitive landscape & strategies of key players
• Potential & niche segments and regions exhibiting promising growth covered
• Historical, current, and projected market size, in terms of value
• In-depth analysis of the Next Generation Sequencing Sample Preparation Market

Overview of the regional outlook of the Next Generation Sequencing Sample Preparation Market:

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.

Highlights of The Next Generation Sequencing Sample Preparation Market Report:

1. The market structure and projections for the coming years.
2. Drivers, restraints, opportunities, and current trends of Next Generation Sequencing Sample Preparation Market.
3. Historical data and forecast.
4. Estimations for the forecast period 2028.
5. Developments and trends in the market.

                1. Automated Library Preparation

7. Market scenario by region, sub-region, and country.
8. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
9. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
10. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Next Generation Sequencing Sample Preparation Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.

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Reasons to Purchase the Next Generation Sequencing Sample Preparation Market Report:

• The report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period
• Segments and sub-segments include quantitative, qualitative, value (USD Million,) and volume (Units Million) data.
• Regional, sub-regional, and country level data includes the demand and supply forces along with their influence on the market.
• The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
• Comprehensive companies offering products, relevant financial information, recent developments, SWOT analysis, and strategies by these players.