In 2016, the global market for large- and small-scale bioprocessing (biopharmaceutical production) was valued at USD 26.12 million. The potential of bioprocess engineering in the development of biopharmaceuticals has been explored and has opened up lucrative opportunities for contract manufacturing companies (CMOs) and bio manufacturers. This will attract targeted efforts to increase market acceptance of different bioprocess engineering solutions.
In the next few years, the lucrative revenue stream from the pharmaceutical industry will be derived from biopharmaceuticals manufacturing. The bioprocessing market will also grow significantly due to the shift in the pharmaceutical industry towards biopharmaceuticals.
The biopharmaceutical manufacturing sector has seen rapid progress in bioprocess engineering. This includes the development of single-use technology and contract services. Nano-biocatalysts are a new innovation that aims to speed up turnaround times and increase enzyme activity to boost bioproduction. This will lead to increased revenue generation.
Only a few firms could manage the entire value chain for large-molecule bioproduction. The technological advancements in bioprocessing technology have made it possible for many companies to be involved in developing biologics and biosimilars.
Due to the high demand for biopharmaceuticals suppliers have expanded their product range for biomanufacturing. Bioreactor suppliers and other ancillary equipment for bioprocessing are making efforts to meet growing demands from bio manufacturers regarding cost, space, portability, and cost.
Budgets for biomanufacturing are increasing in all aspects. Companies are observed making significant investments in biomanufacturing-related R&D. This also includes hiring expert professionals and expansion of manufacturing capacity. These factors will play an important role in the reshaping of bioprocessing for various products.
The introduction of data analysis and high-throughput process development services allows entities to gain insight into product production and optimize the entire process. Bioprocessing equipment has been embraced more because of its promise to be a cost-effective solution for heavy metal contamination.
This market is expected to grow significantly in the future, but there are likely to be some limitations to its growth. These include environmental and purification issues related to protein production, as well as concerns regarding single-use bioprocessing equipment.
Bioprocessing involves three steps: upstream processing and fermentation. The downstream processing is based on activities that are performed to convert crude raw material into final product.
Purification of product is a key step in downstream processing and is therefore the most difficult and crucial step. It requires more attention. This has led to a large share in this market segment in 2016.
Furthermore, bioprocessing engineering advancements directly impact the production yield. This position, in turn, places the downstream processing segment at the center of major big pharma stakeholder.
The advent of single-use technology and the growth in mammalian production titer will both drive upstream processing to a profitable pace over the forecast period. In the future, revenue growth is expected to be accelerated by technological improvements in fermenters and bioreactors.
Due to their high usage rate and large-scale bioproduction needs from key industry players, bioreactors accounted a significant share of revenue inflow. Automated cell culture using specialized bioreactors is crucial for the development and promotion of value-added products.
This market will see a rise in revenue due to the availability of many bioreactors that can be customized according to their operation mode, phase type, capacity, fluid flow type, or use type. This market also includes bags & containers as well as filtration assemblies and cell culture products.
Cell culture products are the fastest growing segment. This is due to ongoing advances in cell line development, including the creation of recombinant cells. This segment is expected to grow because of the production of biopharmaceutical-derived cell lines from mammalian cells.
The commercial success of biologics and biosimilars for clinical usage in the current environment accounted for the largest share of the biopharmaceuticals and biotherapeutics production. Bioprocess engineering is being used by pharmacists to create organism-derived therapeutics. This will in turn drive growth.
Companies are also involved in increasing their manufacturing capabilities for biopharmaceutical research, which is expected to lead to lucrative growth. This market also has applications in bioremediation and biorefineries, as well as microbial biomass, biofuels, microbial metabolism, bioremediation and biorefineries.
Bioprocessing can be divided into two broad categories depending on the amount of culture produced. The small-scale bioreactor system allows parallel processing and allows for the evaluation of several experiments to optimize bioprocesses. This is expected to support the growth of small-scale bioprocessing.
In 2016, the largest market share was held by industrial bioprocessing for pharmaceutical development. The market is constantly introducing new techniques and tools that support industrial-scale Bioprocessing. This has helped to accelerate industrial-scale Bioprocessing applications.
In June 2016, GE Healthcare launched Capto Q XP chromatography material. These chromatography resins can be used as strong anion exchangers to purify large-scale industrial biomolecules. These initiatives will positively impact the growth of the segment during the forecast period.
This market has both single-use and multiple-use products. The fastest growth is expected for single-use product-based Bioprocessing during the forecast period. This segment is expected to see significant growth due to the demand for single-use products.
Single-use products have many advantages that will increase their popularity. One of the major benefits associated with single-use products is the reduction in additional costs associated with assembly, cleaning and process validation.
In terms of revenue generation, multiple-use products for bioprocessing dominated 2016's market. Its large market share is due to the low environmental impact of multi-use instruments and the one-time investment.
In-house biomanufacturing has risen in 2016 due to the presence of international players who are well-established and capable of producing biopharmaceuticals.
One of the main reasons for keeping manufacturing in-house is the complexity of biologics. Companies are also using their own capabilities to protect their product development processes.
The future market will see the outsourcing model of manufacturing grow in value. This is due in large part to the significant increase in budgets for outsourcing biomanufacturing.
Outsourcing can also be a lucrative option due to factors like lack of expertise and limited ability to perform industrial-scale bioprocess application.
The above illustration shows that North America is the largest market, accounting for 27.34% overall market revenue share in 2016. This region is a leader in revenue generation due to its focus on cutting-edge R&D in Biomanufacturing.
The region's progress is also influenced by the development of infrastructure and the availability of funds for bioprocessing technology. This segment is also helped by the presence of large numbers of biomanufacturing plants in the region.
Asia Pacific will be the region with the highest market potential in the future. Many companies have begun to outsource biologics manufacturing and clinical trials in the region, which is a key factor in driving progress in this area.
Some prominent players operating in the market include Merck KGaA (Sigma-Aldrich Co. LLC), Thermo Fisher Scientific, Inc.; Corning, Inc.; Sartorius AG; CESCO BIOENGINEERING Co., Ltd.; Bio-Process Group; Bioprocess Control AB; Eppendorf AG; Applikon Biotechnology; Lonza; PBS Biotech, Inc; Finesse; Binex Co., Ltd.; Meissner Filtration Products, Inc.; CMC Biologics; CellGenix GmbH; Boehringer-Ingelheim; Patheon; Samsung Biologics; Rentschler Biotechnologie GmbH; TOYOBO Co., Ltd, and Inno Biologics Sdn Bhd.
These companies are taking strategic initiatives to maintain their share and increase industrial share. Companies have taken strategic initiatives to improve their product lines, strengthen their distribution networks, collaborate with other companies, and merge & acquire.
Finesse Solutions, Inc, for example, launched the single-use, 3-liter SmartVessel bioreactor vessel SmartVessel in November 2016. This vessel is designed to be used for biofuels and fermentation. This move is expected to improve the company's standing in the future.
Attribute |
More Details |
Base year for estimation |
2016 |
Actual estimates/Historical data |
2014 - 2016 |
Forecast period |
2017 - 2025 |
Representation of the market |
Revenues in USD Billion, and CAGR between 2017-2025 |
Regional scope |
North America, Europe and Asia Pacific, Latin America, Middle East, & Africa |
Country coverage |
U.S., Canada, Germany, France, China, India, Brazil, South Africa |
Report coverage |
Forecast revenue, company share, competitive landscape and growth factors and trends |
15% customization free (equivalent of 5 Analyst working day) |
We will customize the report to provide you with specific market information that is not included in the current report. |
This report predicts revenue growth at the global, regional and country levels. It also analyzes the industry trends for each sub-segment from 2014 through 2025. Grand View Research has divided the global large-scale and small-scale bioprocessing market (biopharmaceutical manufacturing), based on product, region, use-type, scale, and application.
Scale Outlook (Revenue, USD Billion, 2014 - 2025)
Industrial Scale (Over 50,000 Litre)
Small scale (Less Than 50,000 Litres)
Workflow Outlook (Revenue USD Billion, 2014-2025)
Downstream Processing
Fermentation
Upstream Processing
Product Outlook (Revenue, USD Billion, 2014 - 2025)
Bioreactors/Fermenters
Cell Culture Products
Filtration Assemblies
Accessories for Bioreactors
Bags & containers
Other
Application Outlook (Revenue, USD Billion, 2014 - 2025)
Biopharmaceuticals
Specialty Industrial Chemicals
Environmental Aids
Use-type Outlook (Revenue, USD Billion, 2014 - 2025)
Multi-Use
Single-Use
Mode Outlook (Revenue, USD Billion, 2014 - 2025)
In-house
Outsourced
Regional Outlook (Revenue USD Billion, 2014-2025)
North America
The U.S.
Canada
Europe
Germany
France
Asia Pacific
China
India
Latin America
Brazil
Middle East & Africa
South Africa
Up Market Research published a new report titled “Large & Small-Scale Bioprocessing Market research report which is segmented by Mode (In-house, Outsourced), by Use-type (Single-use, Multi-use), by Workflow (Downstream, Fermentation, Upstream), By Players/Companies Small scale (Less than 50000 Litre), Scale Outlook (Revenue USD Billion 2014 - 2025)Industrial Scale (Over 50000 Litre)Small scale (Less than 50000 Litre), Industrial Scale (Over 50000 Litre)”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.
Report Attributes | Report Details |
Report Title | Large & Small-Scale Bioprocessing Market Research Report |
By Mode | In-house, Outsourced |
By Use-type | Single-use, Multi-use |
By Workflow | Downstream, Fermentation, Upstream |
By Companies | Small scale (Less than 50000 Litre), Scale Outlook (Revenue USD Billion 2014 - 2025)Industrial Scale (Over 50000 Litre)Small scale (Less than 50000 Litre), Industrial Scale (Over 50000 Litre) |
Regions Covered | North America, Europe, APAC, Latin America, MEA |
Base Year | 2020 |
Historical Year | 2018 to 2019 (Data from 2010 can be provided as per availability) |
Forecast Year | 2028 |
Number of Pages | 213 |
Number of Tables & Figures | 150 |
Customization Available | Yes, the report can be customized as per your need. |
The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.
The market is segmented by Mode (In-house, Outsourced), by Use-type (Single-use, Multi-use), by Workflow (Downstream, Fermentation, Upstream).
Large & Small-Scale Bioprocessing Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.
Key Benefits for Industry Participants & Stakeholders:
Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.
We have studied the Large & Small-Scale Bioprocessing Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.
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