Global G-Protein Coupled Receptors (GPCRs) Market by Application (Cancer Research, Inflammation Research), by Product (Detection Kits, Cell Lines) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast To 2028

Industry Insights

Global G-protein coupled receptors market was valued at USD 2.60 Billion in 2018. It is expected to grow at 6.7% CAGR between 2019 and 2026. GPCRs can respond to many external stimuli and are a part of many disease etiologies. The wide application of various techniques such as High-Throughput Screening, combinatorial chemistry and medicinal chemistry has allowed for the identification of ligands which modulate the target’s activity.

This has led to the identification of drug candidates that are pharmaceutically relevant, which in turn drives their adoption in drug discovery. These receptors are being targeted by a large number of approved drugs as well as drugs that have been tested in clinical and preclinical trials. This increases the need for GPCR screening tests in drug development. These assays are also in demand because of the increasing availability of biological drugs and allosteric modators that target these receptors.

The development of effective drug discovery methods is possible thanks to advances in computational approaches that streamline receptor structures. Researchers from the University of Southern California and the Skolkovo Institute of Science & Technology developed a thermally stable GPCR using a computational method to formulate new drugs.

Market companies are more focused on the research necessary to discover novel biological functions for the withdrawn and approved drug candidates. This will allow them to be used in other indications. Arena Pharmaceuticals' research has found a relative expression of over seven hundred receptors that are of high therapeutic significance. This research could be used to discover small molecules.

Product Insights

In 2018, the cell line market had the highest revenue share due to the availability of a wide range of cell types. The estimated revenue share is due to cell lines playing a significant role in the cellular-impedance assays used for GPCR target detection. The popularity of detection kits has increased in recent years due to their ease-of-use, robust and high-sensitivity products that can evaluate activity through various pathways. The segment is expected to grow due to the introduction of non-labelled detection systems such as resonance waveguide grating and impedance-based sensor.

Assay Type Insights

CAMP assays had the highest revenue share due to the fact that cyclic Adenosine Monophosphate is an intracellular second messenger involved in GPCR signal transduction. The segment is also driven by the availability of a wide product portfolio in terms of reagent kit for measuring cAMP messenger levels. The segment of calcium functional assays is expected to see the highest CAGR between 2019 and 2026. This is due to the many benefits associated with calcium flux assays such as high sensitivity and ease in estimating calcium flux.

Application Insights

Many applications can be associated with GPCR activity. This is useful for treating a variety of disorders. GPCR activity is associated with the majority of immunotherapy-related detections and tumor angiogenesis. GPCR activity is a ubiquitously expressed protein that facilitates intercellular communication and opens the door to potential therapeutics.

GPCR assays are a great way to generate substantial income in cancer research. Numerous studies have shown that GPCR activity can reveal the characteristics of cancer patients, including their tumor growth, invasiveness and metastasis. According to the research, every type of cancer cell/tumor expresses a similar set of GPCR. It was also found that more than 150 different GPCRs were expressed in some cell types, with one being expressed at a relatively high level.

This identifies biomarker-based research in this sector, which leads to the development of lead candidate GPCRs. Over the past years, this receptor's role has been increasingly recognized in the field of inflammation research. G-protein-coupled receptor kinases regulate signaling pathways such as the nuclear factor?B signaling pathway. This pathway is linked to various inflammatory processes. These signaling pathways can be used as therapeutic targets in inflammatory diseases.

Regional Insights

North America dominated the global GPCR market in 2018. This was due to its strategic investments in cancer research and approval of GPCR-targeted medicines. It also increased emphasis on drug discovery and development activities. In the U.S. and European Union, 134 GPCR targets for drugs had been approved in November 2017. 128 targets were also listed in FDA's orange book. Due to the presence of many emerging companies such as Sosei Heptares and HD Biosciences Co. Ltd., Asia Pacific will be the fastest growing regional market in the future. Regional growth is driven by the number of initiatives taken by companies to increase their market presence.

Market Share insights for G-Protein Coupled Rectors

Thermo Fisher Scientific, Inc., Eurofins Scientific, QIAGEN, WuXi AppTec (HD Biosciences Co. Ltd); Promega Corporation, Abcam plc, Perkin Elmer Inc. (Cisbio Bioassays); Enzo Biochem Inc., Merck KGaA, and Becton-Dickinson and Company are some of the key players in the GPCRs Market.

These companies use a variety of strategies to keep their market share. They are also integrating innovative technologies and automation with drug development screening procedures in order to increase their therapeutic production capabilities.

The Report Covers Certain Segments

This report provides a forecast of revenue growth at the global, regional, or country level and also analyzes the most recent industry trends in each sub-segment from 2015 to 2026. Up Market Research has divided the global G protein coupled receptors market report by product, assay type and application.

• Product Outlook (Revenue USD Million, 2015-2026)

  • Cell Phones

  • Detection kits

  • Cell Culture Reagents

  • Ligands

• Assay Type Outlook (Revenue USD Million, 2015-2026)

  • cAMP Functional Assays

  • Calcium Functional Assays

  • ?-Arrestin Functional assays

  • Radioligand Binding and Functional Assays with GTP?S

  • Internalization Assays

  • Trafficking Assays

  • Other Assays

• Application Outlook (Revenue USD Million, 2015-2026)

  • Cancer Research

  • CNS Research

  • Metabolic Research

  • Cardiovascular Research

  • Respiratory Research

  • Inflammation Research

  • Other Applications

• Regional Outlook (Revenue USD Million, 2015-2026)

  • North America

    • U.S.

    • Canada

  • Europe

    • Germany

    • U.K.

  • Asia Pacific

    • China

    • India

    • Japan

  • Latin America

    • Brazil

  • Middle East and Africa (MEA).

    • South Africa

These are the most frequently asked questions about this report

b. Global G-protein coupled receptors market was valued at USD 2.8 billion in 2019, and is forecast to grow to USD 3.0 billion by 2020.

b. Global G-protein Coupled Receptors Market is expected to grow at 6.7% compound annual growth rate between 2019 and 2026, reaching USD 4.4 billion in 2026.

b. Thermo Fisher Scientific, Inc., Eurofins Scientific, QIAGEN, WuXi AppTec(HD Biosciences Co. Ltd); Promega Corporation, Abcam plc, Perkin Elmer Inc. (Cisbio Bioassays); Enzo Biochem Inc., Merck KGaA, and Becton-Dickinson and Company are some of the key players in the G-protein-coupled receptors market.

b. Market growth opportunities include advances in understanding GPCR biology in oncology to develop combined therapies and technological advancements.

b. The market growth is being driven by several factors: growing demand for GPCR assays for drug discovery studies; widespread application of GPCRs for treatment of various medical conditions; and the increasing number of initiatives taken by the government and other key players.

Up Market Research published a new report titled “G-Protein Coupled Receptors (GPCRs) Market research report which is segmented by Application (Cancer Research, Inflammation Research), by Product (Detection Kits, Cell Lines), By Players/Companies Thermo Fisher Scientific, Inc; Eurofins Scientific; QIAGEN; WuXi AppTec(HD Biosciences Co Ltd); Promega Corporation; Abcam plc; Perkin Elmer Inc(Cisbio Bioassays); Enzo Biochem Inc; Merck KGaA; and Becton-Dickinson and Company”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.

Report Scope

The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.

Global G-Protein Coupled Receptors (GPCRs) Market Report Segments:

The market is segmented by Application (Cancer Research, Inflammation Research), by Product (Detection Kits, Cell Lines).

G-Protein Coupled Receptors (GPCRs) Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.

Key Benefits for Industry Participants & Stakeholders:

• Industry drivers, restraints, and opportunities covered in the study
• Neutral perspective on the market performance
• Recent industry trends and developments
• Competitive landscape & strategies of key players
• Potential & niche segments and regions exhibiting promising growth covered
• Historical, current, and projected market size, in terms of value
• In-depth analysis of the G-Protein Coupled Receptors (GPCRs) Market

Overview of the regional outlook of the G-Protein Coupled Receptors (GPCRs) Market:

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.

Highlights of The G-Protein Coupled Receptors (GPCRs) Market Report:

1. The market structure and projections for the coming years.
2. Drivers, restraints, opportunities, and current trends of G-Protein Coupled Receptors (GPCRs) Market.
3. Historical data and forecast.
4. Estimations for the forecast period 2028.
5. Developments and trends in the market.

                1. Cancer Research

                2. Inflammation Research

                1. Detection Kits

                2. Cell Lines

8. Market scenario by region, sub-region, and country.
9. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
10. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
11. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the G-Protein Coupled Receptors (GPCRs) Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.

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Reasons to Purchase the G-Protein Coupled Receptors (GPCRs) Market Report:

• The report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period
• Segments and sub-segments include quantitative, qualitative, value (USD Million,) and volume (Units Million) data.
• Regional, sub-regional, and country level data includes the demand and supply forces along with their influence on the market.
• The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
• Comprehensive companies offering products, relevant financial information, recent developments, SWOT analysis, and strategies by these players.