Global Controlled Release Drug Delivery Market by Technology (Micro Encapsulation, Targeted Delivery) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast To 2028

Summary of the Report

Global controlled release drug delivery market was worth USD 37.8 million in 2019. It is expected to grow at 7.8% CAGR over the forecast period. The key growth drivers are changing prescription patterns and a preference for controlled release systems by physicians over conventional drug delivery systems. The growth is expected to be driven by benefits such as higher therapeutic efficacy, improved patient compliance and lower treatment costs. Pharmaceutical companies, which are part of a fragmented and highly competitive market, are proactive in adapting to changing needs and investing in controlled release drug delivery systems. This will significantly drive the demand.

Market growth is expected to be boosted by the constant increase in R&D spending by pharmaceutical companies for developing effective therapy for chronic and other non-communicable conditions like cancer, diabetes, and high blood pressure. Taris, a biomedical company based on R&D, has TAR-200 (Gemcitabine), a pipeline product that is indicated for treatment of bladder cancer. It uses a controlled drug delivery system. Johnson & Johnson will acquire Taris Biomedical by 2020. This transaction is being encouraged by TAR-200, the company's leading investigational product.

The market is experiencing significant growth due to the rising geriatric population and the growing number of children. Geriatrics have compromised biological, physical and mental functions, which can affect their medication intake. Their bodies are unable to tolerate harsh side effects and high doses of drug. With a rapidly growing patient population, controlled release drug delivery systems will be in high demand.

Controlled drug delivery can be used to reduce doses and frequency, avoid abnormal fluctuations in plasma drug levels, increase efficacy, increase patient compliance and ensure uniform drug effects. Control releases drug delivery systems deliver drug to the targeted site at a predetermined time and with predictable drug release kinetics. This is in contrast to traditional delivery systems. The controlled release delivery system has many benefits that will increase their popularity over the next few years.

Technology Insights

Technology has divided the controlled drug delivery market into Wurster technique and coacervation. In 2019, targeted delivery dominated the market because a lot of market participants have strong portfolios for the technology. Targeted delivery can be used to avoid drug toxicity and offers a preferred site of action. Targeted delivery systems offer increased bioavailability. This allows for better absorption and lower fluctuations in drug levels. It is a popular drug delivery method.

The microencapsulation segment is expected to grow over the forecast period due to rising demand for highly complex and unstable molecules like vitamins, proteins, and antioxidants. Microencapsulation can increase the shelf life of vitamin A, which is notorious for its low water solubility, chemical stability, and controlled drug release.

Implantable systems offer improved efficiency, decreased side-effects and convenience. They also ensure the delivery of drugs in a linear fashion over a set period. Coacervates are a new class of drug delivery vehicles that can carry small molecules of drugs and proteins. These include coacervates containing heparin and synthetic polycations that allow controlled delivery of growth factors. They are expected to gain significant market share due to their increasing use.

Application Insights

The market is divided into injectables and Drug eluting Stents. Oral controlled, transdermal, and ocular patches. Infusion pumps and metered dose inhalers. Due to its availability and frequent usage, the oral controlled segment was the largest revenue contributor in 2019.

Another lucrative segment is the metered dose inhaler, which is expected to grow at a substantial CAGR during the forecast period. The segment will grow due to rising prevalence of respiratory diseases, new products, and technological advances. Gofire Inc., a medical tech company, introduced a metered-dose inhaler in 2019 This product has a unique dose completion signal that ensures accurate dosing. Aradigm Corporation currently has three products in its pipeline for the treatment of bronchiectasis and cystic fibrosis. The product also includes a unique dose completion alert signal. Metered dose inhalers are easier to administer drugs than other methods.

Due to their wide range of products and use in the treatment of many diseases, injectables held a large market share in 2019. Long-acting injectables offer many advantages over conventional delivery methods. They have a predictable drug release profile for a defined time period, increased patient compliance, better systemic availability of drugs and ease of application. This helps to reduce medical expenses.

Release Mechanism Insights

The market can be divided by release mechanism into micro reservoir feedback regulated, activation modulated and partition controlled. A large share of the market was dominated by feedback-regulated drug delivery systems in 2019, due to their effectiveness in treating disorders like diabetes. The market will grow due to increased R&D activities to maximize the potential of feedback-regulated controlled drug delivery system as antidotes.

There are three types of chemically activated systems: pH activated, enzyme activated and hydrolysis activated. This segment's growth is driven by its ability to quickly and precisely respond to the metabolite that interests it. An enzyme activated release mechanism allows for controlled and optimal insulin release in hyperglycemic patients.

The popularity of chemically activated delivery systems has increased dramatically. To expand their product range, market players are investing in this segment. Pfizer, Inc. markets QuilliChew ER chewable tablet and LYRICA Pregabalin. These are controlled release, chemically activated delivery system that provide controlled release. This segment is expected to account for a significant market share over the forecast period.

Regional Insights

North America was the largest regional market in 2019, Regional market growth will be supported by government initiatives to develop controlled release drug delivery and growing investments in R&D. The presence of market leaders is also helping to promote product adoption. The market is growing due to the rising incidence of chronic diseases like diabetes, cancer, and heart disease. The key trend driving regional market growth is the increasing use of systems to treat hypertension.

Europe held the second largest market share for 2019 due to the presence of large pharmaceutical companies and increased R&D. The region's market for chronic diseases like cancer, diabetes and chronic obstructive pulmonary disease (COPD) is expected to continue its healthy growth trajectory in the coming years.

Asia Pacific will likely see the largest CAGR over the forecast period. Due to the rapid development of the pharmaceutical industries in India and China, this region is gaining international attention. Another factor that has influenced product adoption is the large Japanese geriatric population.

Market Share in Controlled Release Drug Delivery

Orbis Biosciences, Inc., Merck and Co., Inc., Johnson and Johnson, Coating Place, Inc., Corium International, Inc., Depomed, Inc., Pfizer, Inc., Aradigm Corporation, and Capsugel are key market players. As several drug developers work to develop drugs that meet specific patient needs, the market is fragmented.

Many companies use a variety of technologies to ensure controlled release. Controlled release is a major strategy used by pharmaceutical companies to expand their product penetration and consumer base. The market is crowded with players who are competing fiercely against each other and new entrants.

Key players also use mergers and acquisitions as a way to increase their product portfolios. Capsugel, for example, announced in January 2016 that it had acquired Powdersize and Xcelience. This helped the company expand its resources within its dosage form solutions segment.

Other major players are also involved in the development of controlled release drug delivery technology. Capsugel, for example, announced the launch of enTRinsic, a drug delivery system that offers complete enteric protection and targeted release into the upper gastrointestinal tract. This technology allows for a wide range of compounds to be delivered.

Controlled Release Drug Delivery Market Report Scope

The Report Covers Certain Segments

This report predicts revenue growth at the global, regional and country level and offers an analysis of industry trends for each sub-segment from 2016 to 2027. Grand View Research divided the global controlled-release drug delivery market report based on technology, release mechanism and application.

• Technology Outlook (Revenue USD Million, 2016-2027)

  • Wurster Technique

  • Coacervation

  • Micro Encapsulation

  • Implants

  • Transdermal

  • Targeted delivery

  • Other

• Release Mechanism Outlook (Revenue USD Million, 2016-2027)

  • Systems based on polymers

  • Micro Reservoir Partition Controlled Drug Delivery Systems

  • System for Drug Delivery Regulations - Feedback

  • Drug Delivery Systems that are activated-modulated

    • Osmotic Pressure Activated

    • Hydrodynamic Pressure Activated

    • Vapor Pressure Activated

    • Mechanically activated

    • Magnetically activated

  • Chemically activated

    • pH activated

    • Hydrolysis activated

    • Enzyme activation

• App Outlook (Revenue USD Million, 2016-2027)

  • Metered dose inhalers

  • Injectable

  • Transdermal and Ocular patches

  • Infusion pumps

  • Oral controlled drug delivery systems

  • Drug-eluting Stents

• Regional Outlook (Revenue USD Million, 2016-2027)

  • North America

    • The U.S.

    • Canada

  • Europe

    • Germany

    • The U.K.

    • France

    • Italy

    • Spain

    • Netherland

    • Switzerland

    • Russia

    • Belgium

    • Sweden

  • Asia Pacific

    • China

    • Japan

    • India

    • Thailand

    • South Korea

    • Indonesia

    • Philippines

    • Vietnam

    • Singapore

    • Malaysia

  • Latin America

    • Brazil

    • Mexico

    • Argentina

    • Colombia

    • Chile

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait

    • Israel

These are the most frequently asked questions about this report

b. Global controlled release drug delivery market was valued at USD 40.62 Billion in 2019, and is forecast to grow to USD 46.01 Billion by 2020.

b. Global controlled release drug delivery market will grow at a compound annual rate of 14.8% between 2020 and 2027, reaching USD 120.73 billion in 2027.

b. With a 43.47% share in 2019, North America was the dominant market for controlled release drug delivery. This is due to the increasing burden of chronic diseases like cancer, diabetes, and heart disease.

b. Orbis Biosciences, Inc., Merck and Co., Inc., Johnson and Johnson, Coating Place, Inc., Corium International, Inc., Depomed, Inc., Pfizer, Inc., Aradigm Corporation, and Capsugel are some of the key players in the controlled-release drug delivery market.

b. Market growth is being driven by key factors such as physicians' increasing preference for controlled release systems due to their benefits of high-therapeutic efficacy and better patient compliance.

Up Market Research published a new report titled “Controlled Release Drug Delivery Market research report which is segmented by Technology (Micro Encapsulation, Targeted Delivery), By Players/Companies Inc; Depomed, Orbis Biosciences, Inc; Corium International, Inc; Pfizer, Inc; Merck and Co, Inc; Aradigm Corporation; and Capsugel, Inc; Alkermes plc; Johnson and Johnson; Coating Place”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.

The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.

Global Controlled Release Drug Delivery Market Report Segments:

The market is segmented by Technology (Micro Encapsulation, Targeted Delivery).

Controlled Release Drug Delivery Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.

Key Benefits for Industry Participants & Stakeholders:

• Industry drivers, restraints, and opportunities covered in the study
• Neutral perspective on the market performance
• Recent industry trends and developments
• Competitive landscape & strategies of key players
• Potential & niche segments and regions exhibiting promising growth covered
• Historical, current, and projected market size, in terms of value
• In-depth analysis of the Controlled Release Drug Delivery Market

Overview of the regional outlook of the Controlled Release Drug Delivery Market:

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.

Highlights of The Controlled Release Drug Delivery Market Report:

1. The market structure and projections for the coming years.
2. Drivers, restraints, opportunities, and current trends of Controlled Release Drug Delivery Market.
3. Historical data and forecast.
4. Estimations for the forecast period 2028.
5. Developments and trends in the market.

                1. Micro Encapsulation

                2. Targeted Delivery

7. Market scenario by region, sub-region, and country.
8. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
9. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
10. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Controlled Release Drug Delivery Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.

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Reasons to Purchase the Controlled Release Drug Delivery Market Report:

• The report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period
• Segments and sub-segments include quantitative, qualitative, value (USD Million,) and volume (Units Million) data.
• Regional, sub-regional, and country level data includes the demand and supply forces along with their influence on the market.
• The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
• Comprehensive companies offering products, relevant financial information, recent developments, SWOT analysis, and strategies by these players.