Global Brain PET-MRI Systems Market by Phase (Pre-clinical, Clinical), by Product (Helium Free System, Traditional System) and Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast To 2028

Summary of the Report

Global brain PET-MRI system market was worth USD 281.1 million in 2019. It is projected to grow at a compound annual rate (CAGR of 5.1%) between 2020 and 2027. Because it provides high-resolution, 3-dimensional imaging of molecular, functional and physiologic targets, Positron emission technology (PET), is a popular choice for neurological applications. PET technology has the advantage of imaging the entire brain. However, PET images lack spatial resolution and are sensitive and insufficiently attenuated. They also need scatter correction. PET devices can be combined with other imaging devices, mainly magnet resonance imaging (MRI), to address these issues. This allows for precise correspondence with anatomic structures and pathologic changes.

The combination of MRI and PET is considered to be one of the most efficient hybrid imaging systems in neurology. Its ability to image the brain's morphology and the presence of MRI modalities to assess physiologic or metabolic parameters such as perfusion, edema and vascular supply will likely encourage its adoption. Combining information from MRI with PET hybrid imaging system allows for enhanced diagnosis of neurological conditions.

Brain PET-MRI systems offer new possibilities in multiparametric neuroimaging. They simultaneously observe the biochemical and physiological processes of the brain. The device is being used in a variety of medical settings. According to NCBI, approximately 30 PET-MRI scanners had been installed in the United States by March 2017. Companies are also conducting studies to determine the effectiveness of MRI PET scanners on humans and animals.

Preclinical imaging using brain PET-MRI systems is steadily increasing. This is opening up new opportunities for players. Aspect Imaging partnered up with Seoul National University in September 2016 to launch Preclinical PETMRI Complete Solution at the World Molecular Imaging Congress, (WMIC), in New York. This system combines Aspect Imaging's compact MRI M7 and the SNU new PET insert "SimPET". This device is now commercially available and scientists can conduct research in many fields, including neurology.

Despite the many benefits of brain PET-MRI systems for neurology, it is not without its challenges. Combining PET MRI units is not easy. The main challenges include the placement of PET system with photomultiplier tube (PMTs), proper construction of PET MRI system and creating attenuation maps to PET images. PET detector elements can cause problems around the magnetic field, which in turn affects the device's performance. This issue is being addressed by current measures. This includes the use of optical fibers to shield PMT from the magnetic fields, the protection of PMT from the magnet field and the usage of avalanche-photodiode (APDs), instead of PMT. Market growth may be affected by the difficulties in creating a PET-MRI system that works.

Phase Insights

Pre-clinical PET-MRI systems accounted for 55.6% of the total revenue in 2019. This is due to the high number of studies that have been conducted on the device in order to understand its effectiveness in diagnosing neurological disorders. Market players are also developing preclinical brain PETMRI systems in order to gain market share or maintain their position in the market. Aspect Imaging, Bruker, Mediso Ltd., MR Solutions and Cubresa Inc. are just a few of the market players that have pre-clinical PETMRI devices for neurology.

Alliances are being formed by players to increase the reach of pre-clinical PET-MRI systems for brain. Aspect Imaging and Brightonix Imaging formed an alliance in September 2018 to offer SimPET inserts to preclinical MRI researchers. The insert can be used with MRI machines with a 16 cm to 40cm bore size and a 3.0 T to 11.74T field strength. This preclinical PET-MRI system will be useful for researchers in many fields, including neurology, cardiology and oncology.

The fastest growth rate for clinical brain PET-MRI systems is 6.6% over the forecast period. Segment growth will be supported by an increasing number of clinical trials for neurological diseases. Currently, there are more than 299 clinical trials of brain PET-MRI systems to diagnose neurological disorders. Pre-clinical brain PETMRI systems for neurological disorders are also showing promising results and are now entering the clinical phase. These clinical trials are expected to result in the launch of PETMRI devices for neurology. This will increase the market's growth. Siemens Healthcare, one of the major players in the market, has also launched PET-MRI systems for use in neurology and other clinical applications. Market growth is expected to be boosted by the increasing number of clinical trials and the launch PET-MRI systems for brain.

Product Insights

The market's increasing development of traditional PET-MRI devices led to a 60.8% revenue share for this device in 2019. Players like GE Healthcare and Siemens Healthcare have developed traditional brain PET-MRI systems. These systems use helium to cool down the magnet. The installation of these MRI machines is complicated by the use of helium. This will have an impact on the forecast period's growth.

The fastest growth rate for helium-free brain PET/MRI systems is 5.6% over the forecast period. These devices are expected to be more popular because of the associated cost of helium. Market players are focusing their efforts on developing helium-free brain PET/MRI systems to avoid the problems associated with older brain PET/MRI systems. MR Solutions and GE Healthcare, two market players, are focusing their efforts on the development of helium free MRI machines that can later be integrated with PET systems in order to create a heliumless PET-MRI machine. These players are currently developing preclinical helium free brain PET-MRI systems in order to study its effectiveness in neurology.

MR Solutions developed a dual-field 3T/7T PET/MR scanner that was helium-free and suitable for molecular research. This device was installed by universities and institutes like the Mallinckrodt Institute of Radiology at Washington University School of Medicine to conduct research in the fields of oncology, neurology, and cardiology. This helium-free system from MR Solutions was presented at the World Molecular Imaging Congress in September 2019. It was used for preclinical research. To increase adoption of helium free brain PET-MRI systems, the company also expanded its distribution network in Japan Korea, Australia, China, and Australia. The market will see increased interest from market players in developing and studying helium-free PET-MRI systems for brain development and will therefore impact its commercialization.

End-use Insights

The increasing number of neurological disorders means that hospitals held 42.2% of the total revenue share in 2019. Annually, around 500,000 cases are diagnosed with multiple sclerosis, brain tumor and amyotrophiclateral sclerosis. The demand for this diagnosis is increasing due to the increase in neurological cases. To improve the diagnosis of neurological disorders, hospitals have been installing brain PET-MRI scanners. The PET-MRI scanner at Toronto General Hospital was installed in July 2018 for diagnosis of cancer, cardiac diseases, and neurological disorders. Indraprastha Apollo Hospitals also launched the PET-MRI SUITE in February 2013. This suite will house brain PET-MRI systems from different companies, which can be used to diagnose neurology as well as cardiology disorders.

The fastest growth rate for diagnostic imaging centers is 5.4% over the forecast period. Diagnostic imaging centers are preferred by patients with neurological disorders to avoid lengthy wait times and high costs associated with hospitals. These imaging centers are equipped with advanced imaging equipment such as brain PET/MRI systems, which allows for enhanced diagnosis. India's House of Diagnostics has been established to provide PET-MRI scan services. PET-MRI scan includes brain PET-MRI and whole-body PET MRI. DOTA whole body PET MRI is also available. Head and neck FDG PET MRI and whole-body PET MRI for screening for cancer are some of the services offered. Breast only FDG PET MRI is another. The segment is expected to grow due to the increasing focus on diagnostic imaging centers to increase PET-MRI services for various applications, such as neurology.

The forecast period also predicts that the other segment will grow at a rapid pace. For research purposes, universities and research centers are installing pre-clinical PETMRI systems to study the effectiveness of this device in diagnosing neurological disorders. To launch their devices and expand their reach, market players have formed alliances with universities. Aspect Imaging partnered up with Seoul National University's Department of Nuclear Medicine in September 2016 to present a simultaneous preclinical PET/MRI complete solution at this year's World Molecular Imaging Congress (WMIC). The system is commercially available and will allow scientists and researchers to study a variety of fields, including oncology, neurology, and cardiology. The segment will grow as more research is done on brain PET-MRI systems.

Regional Insights

Asia Pacific accounted for 24.2% of the total revenue in 2019, thanks to the growing adoption of advanced diagnostic equipment in universities and research centers in the region. The market will be driven by rising demand from countries like India, Japan and China for diagnostic systems over the forecast period.

North America accounted for 24.0% of the total revenue in 2019, largely because of the increasing prevalence of neurological disorders. According to the American Neurological Association (ANA), the most common neurological disorders in the U.S. are Alzheimer's, stroke, traumatic brain injuries, epilepsy and multiple sclerosis. The prevalence of Alzheimer's disease was 5.3 million in 2017, which is expected to rise over the forecast period. Market players offer brain PET-MRI systems in the U.S. to diagnose neurological disorders. Bruker presented BioSpec 3T PETMRI at the World Molecular Imaging Congress 2015 (WMIC) in September 2015.

In 2019, Europe was responsible for a significant revenue share of the market. The market's revenue share in 2019 was decently represented by Europe. ESHIMT (European Society for Hybrid, Molecular, and Translational Imaging), is a European non-profit organization that coordinates activities in the field hybrid imaging. This non-profit organization also offers training and educational programs to scientists, technologists, physicists, and others interested in advanced hybrid imaging technology.

Market Share Insights & Key Companies

To expand their product range and increase their reach, market players are entering into partnerships and collaborations. Cubresa signed a distribution deal with Worldwide Technology (S.H.). Co., Ltd. will distribute NuPET preclinical imaging product in China. This partnership will improve the research in brain PET-MRI systems in neurology, cardiology and oncology in China.

To enter India and China, market players have formed various alliances. Cubresa is a company that develops PET inserts to MRI. In January 2019, Cubresa joined forces with the GaoXin Group and private investors. They have created the Sino-Canadian Health Engineering Research Institute. This venture aims to create clinical products by Cubresa's BrainPET insert. The insert can be used in 3T and 1.5T MRI systems to provide clinical neurology services. Market growth will be driven by market players' initiatives to develop brain PET/MRI and expand its reach in APAC. The market leader in brain PET-MRI systems is:

• Siemens Healthineers AG

• Koninklijke Philips N.V.

• GE Healthcare

• Bruker

• Mediso Ltd.

• MR Solutions

• Cubresa Inc.

• Aspect Imaging

Up Market Research published a new report titled “Brain PET-MRI Systems Market research report which is segmented by Phase (Pre-clinical, Clinical), by Product (Helium Free System, Traditional System), By Players/Companies Siemens Healthineers AG, Koninklijke Philips NV, Bruker, Cubresa Inc, GE Healthcare, Mediso Ltd, Aspect Imaging, MR Solutions”. As per the study the market is expected to grow at a CAGR of XX% in the forecast period.

Report Scope

The report covers comprehensive data on emerging trends, market drivers, growth opportunities, and restraints that can change the market dynamics of the industry. It provides an in-depth analysis of the market segments which include products, applications, and competitor analysis.

Global Brain PET-MRI Systems Market Report Segments:

The market is segmented by Phase (Pre-clinical, Clinical), by Product (Helium Free System, Traditional System).

Brain PET-MRI Systems Market research report delivers a close watch on leading competitors with strategic analysis, micro and macro market trend and scenarios, pricing analysis and a holistic overview of the market situations in the forecast period. It is a professional and a detailed report focusing on primary and secondary drivers, market share, leading segments and geographical analysis. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report.

Key Benefits for Industry Participants & Stakeholders:

• Industry drivers, restraints, and opportunities covered in the study
• Neutral perspective on the market performance
• Recent industry trends and developments
• Competitive landscape & strategies of key players
• Potential & niche segments and regions exhibiting promising growth covered
• Historical, current, and projected market size, in terms of value
• In-depth analysis of the Brain PET-MRI Systems Market

Overview of the regional outlook of the Brain PET-MRI Systems Market:

Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa (MEA). North America region is further bifurcated into countries such as U.S., and Canada. The Europe region is further categorized into U.K., France, Germany, Italy, Spain, Russia, and Rest of Europe. Asia Pacific is further segmented into China, Japan, South Korea, India, Australia, South East Asia, and Rest of Asia Pacific. Latin America region is further segmented into Brazil, Mexico, and Rest of Latin America, and the MEA region is further divided into GCC, Turkey, South Africa, and Rest of MEA.

Highlights of The Brain PET-MRI Systems Market Report:

1. The market structure and projections for the coming years.
2. Drivers, restraints, opportunities, and current trends of Brain PET-MRI Systems Market.
3. Historical data and forecast.
4. Estimations for the forecast period 2028.
5. Developments and trends in the market.

                1. Pre-clinical

                2. Clinical

                1. Helium Free System

                2. Traditional System

8. Market scenario by region, sub-region, and country.
9. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
10. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
11. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Brain PET-MRI Systems Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2028.

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Reasons to Purchase the Brain PET-MRI Systems Market Report:

• The report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period
• Segments and sub-segments include quantitative, qualitative, value (USD Million,) and volume (Units Million) data.
• Regional, sub-regional, and country level data includes the demand and supply forces along with their influence on the market.
• The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
• Comprehensive companies offering products, relevant financial information, recent developments, SWOT analysis, and strategies by these players.